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Loperamide

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BBFarma srl - Pharmaceutical Trading: A03FA01 - METOCLOPRAMIDE

Objectives To determine whether 10 mg, 25 mg, or 50 mg metoclopramide combined with 8 mg dexamethasone, given intraoperatively, is more effective in preventing postoperative nausea and vomiting than 8 mg dexamethasone alone, and to assess benefit in relation to adverse drug reactions. Design Four-armed, parallel group, double blind, randomised controlled clinical trial. Setting Four clinics of a university hospital and four district hospitals in Germany. Participants patients who received balanced or regional anaesthesia during surgery. Main outcome measures Postoperative nausea and vomiting within 24 hours of surgery primary end point ; occurrence of adverse reactions. The most frequent adverse drug reactions were hypotension and tachycardia, with cumulative incidences of 8. Conclusion The addition of 50 mg metoclopramide to 8 mg dexamethasone given intraoperatively is an effective, safe, and cheap way to prevent postoperative nausea and vomiting.
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Medicines database

Loperamide , sold under the brand name Imodium , among others, [1] is a medication used to decrease the frequency of diarrhea. Common side effects include abdominal pain, constipation , sleepiness, vomiting, and a dry mouth. Loperamide was first made in and used medically in Loperamide is effective for the treatment of a number of types of diarrhea.

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